1324 Court St, Redding, CA 96001 (530) 201-2665
refine · reddingmedical aesthetics & wellness
Mechanism
Triple pathway (GLP-1 + GIP + glucagon)
Also raises energy expenditure
Trial Results
Strongest results so far
In trials to date
FDA Status
Not FDA-approved
Still in clinical trials
Retatrutide vial
Triple Agonist

How It Works


A third pathway, with newer research.

Retatrutide works on the same two hormone pathways as Tirzepatide, GLP-1 and GIP, and adds a third: the glucagon receptor. That third pathway appears to modestly raise how many calories your body burns at rest, on top of turning down appetite.

It’s the newest of the three, with the least long-term data, so we start at a lower dose and raise it in small steps.

Is This Right for Me?

For people who’ve tried the other two.

01

You've plateaued on both Semaglutide and Tirzepatide

A third signaling pathway is the main reason people consider Retatrutide after trying the other two.

02

You want the strongest results shown in trials so far

Retatrutide's trial data currently shows the largest average weight loss of the three medications we offer.

03

You're comfortable with a newer, still-emerging medication

Long-term data is still coming in. You see Nicole monthly, and you can reach her directly when a question or side effect comes up.

Good to Know

What the Retatrutide trials show so far.

Is It Right for You?


Start with a conversation.

Retatrutide isn’t FDA-approved and is still in clinical trials. Ask Nicole whether it’s an option for you. She’ll walk you through how it compares with Semaglutide and Tirzepatide, which have much more research behind them, and what makes sense for your goals.

  • Free 30-minute consult, by phone or in the Studio
  • An honest look at the research and what’s still unknown
  • No pressure to start anything
Free consult
30 minutes with Nicole
Book a Free Consult

Who this isn’t for

Please don’t start Retatrutide if you’re pregnant, breastfeeding, or trying to get pregnant, or if you or a close family member has had medullary thyroid cancer or MEN2 (multiple endocrine neoplasia type 2). In rodent studies, GLP-1 medications caused thyroid C-cell tumors, and no one knows yet whether that happens in people, so those histories rule it out. If you’ve had pancreatitis or gallbladder problems, or you take insulin or another diabetes medication, tell us at your consult so we can talk it through.

If you’d rather stay with a medication that has a longer safety record, Semaglutide or Tirzepatide may suit you better. If you’re hoping to lose a few pounds fast before an event, a monthly program like this probably won’t feel like a good match. Whatever the reason, if it isn’t the right fit, we’ll tell you kindly and help you think through what might work instead.

Not FDA-approved as of October 2026. Results vary from person to person and aren’t guaranteed. This page is general information. Your consult is where we look at your own health history.

Comparing Your Options

Retatrutide next to the other two.

Your dose is set individually, and we’ll talk through your options at your consult. Click a name to read the full page.

Semaglutide Tirzepatide Retatrutide This Page
Mechanism Single pathway (GLP-1) Dual pathway (GLP-1 + GIP) Triple pathway (GLP-1 + GIP + glucagon)
Trial Results ~15% body weight, on average ~20.9% body weight, on average Strongest results so far in trials
Price $285–$400 / mo $285–$800 / mo Discussed at your consult
Best For First-time GLP-1 patients Plateaued on Semaglutide, or want a stronger start Plateaued on the other two, comfortable with a newer option

Good to Know

Retatrutide FAQs

Wondering what’s known so far, or how it compares? Text us at (530) 201-2665.

Is Retatrutide FDA-approved?

Not FDA-approved as of October 2026. It’s the newest of the three, so we start at a lower dose. You get the same monthly check-ins as with the other two, plus direct access to Nicole for questions in between.

Why isn't it available everywhere?

It isn’t FDA-approved, so many providers choose not to offer it yet.

How is it different from the other two?

It adds a third pathway, glucagon receptor activity, on top of the GLP-1 and GIP pathways Tirzepatide already uses. That third pathway appears to modestly raise how many calories you burn, in addition to lowering appetite.

Is it safe?

Trial data so far shows side effects similar to the other two, mostly digestive. It has less long-term data than Semaglutide or Tirzepatide, so tell Nicole about any side effect when you first notice it. You can reach her directly between your monthly check-ins. The same cautions apply as for every GLP-1 medication; see who this isn’t for, above.

Who might consider Retatrutide?

People who've plateaued on Semaglutide or Tirzepatide, or who want the strongest results shown in trials so far and are comfortable with something newer. We'll talk through whether that trade-off makes sense for you at your consult.

What side effects should I expect?

A similar pattern to the other two: nausea, diarrhea, constipation, and tiredness, mostly during dose increases, usually easing as your body adjusts. Call us if you have severe belly pain that won’t let up.

Will insurance cover it?

No. We don’t bill insurance for any of the three medications, Retatrutide included. You’ll know the exact monthly cost before you commit, and Cherry payment plans let you spread it out.

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“I love Nicole! You will too! I am a very happy client!”

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Curious whether Retatrutide makes sense for you?

Book a free 30-minute consult with Nicole. She’ll go over what the research shows so far, what’s still unknown, and how it compares with the other two for your history. By phone Monday through Friday, or in the Studio on Tue or Thu.

Book a Free 30-Min Consult

Curious About Retatrutide?

Start With a Free Consult

Nicole will walk you through whether it’s a fit, how it compares with Semaglutide and Tirzepatide, and what she’d recommend for your goals.

Have a question first? Call or text (530) 201-2665. We’re happy to help before you book.

Get In Touch

Let’s Talk

Questions, or ready to book? Reach out directly, or send a message and we’ll get back to you within 24 hours.

Hours
Mon–Fri9am–4pm by phone & text
Tue & Thu9am–4pm in the Studio
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